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Specifications
- Antibody type:Primary
- Antigen name:Mucin 3
- Clonality:Monoclonal
- Clone:MUC3/1154
- Gene ID:Unigene ID: 744422 , 744530
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Human
- Antigen symbol:MUC3A
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:50 μL
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75963-174
- Supplier No.:BNUM1154-50
Specifications
About this item
This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
Type: Primary
Antigen: MUC3A
Clonality: Monoclonal
Clone: Clone MUC3/1154
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human