About this item
This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Type: Primary
Antigen: MUC3A
Clonality: Monoclonal
Clone: Clone MUC3/1154
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
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Specifications
- Catalog No:
- 75962-278
- 75962-280
- Antigen name:
- Mucin 3
- Mucin 3
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- MUC3/1154
- MUC3/1154
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 744422 , 744530
- Unigene ID: 744422 , 744530
- Isotype:
- IgG2a kappa
- IgG2a kappa