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Specifications
- Antibody type:Primary
- Antigen name:CD45RB
- Clonality:Monoclonal
- Clone:PTPRC/1132
- Gene ID:Unigene ID: 654514
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:PTPRC
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:50 μL
- Western blot:Yes
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75911-620
- Supplier No.:BNUM1132-50
Specifications
About this item
CD45R, also designated CD45 and PTPRC, is identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: Clone PTPRC/1132
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human