To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Antigen name:Beta-2-Microglobulin
- Clonality:Monoclonal
- Clone:B2M/1118
- Gene ID:Unigene ID: 534255
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Non-human primates,Human
- Antigen symbol:B2M
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:50 μL
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75882-074
- Supplier No.:BNUM1118-50
Specifications
About this item
Beta-2 microglobulin is a 12 kDa protein with a pI of 5.6. Serum beta-2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkins lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta-2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Type: Primary
Antigen: B2M
Clonality: Monoclonal
Clone: Clone B2M/1118
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Non-human primates