About this item
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: Clone MCAM/1101
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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Specifications
- Catalog No:
- 75960-706
- 75960-704
- Antigen name:
- MCAM / MUC18 / Mucin 18 / CD146
- MCAM / MUC18 / Mucin 18 / CD146
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- MCAM/1101
- MCAM/1101
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 599039
- Unigene ID: 599039
- Isotype:
- IgG1 kappa
- IgG1 kappa