About this item
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Type: Primary
Antigen: IFNA1
Clonality: Monoclonal
Clone: Clone 2.52
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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Specifications
- Catalog No:
- 75952-002
- 75952-000
- Antigen name:
- Interferon alpha 1
- Interferon alpha 1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- 2.52
- 2.52
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 37026 , 533471
- Unigene ID: 37026 , 533471
- Isotype:
- IgG1 kappa
- IgG1 kappa