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Specifications
- Antibody type:Primary
- Antigen name:Mucin 6
- Clonality:Monoclonal
- Clone:MUC6/916
- Gene ID:Unigene ID: 528432
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:MUC6
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:50 μL
- Western blot:Yes
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75962-950
- Supplier No.:BNUM0916-50
Specifications
About this item
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Type: Primary
Antigen: MUC6
Clonality: Monoclonal
Clone: Clone MUC6/916
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human