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Specifications
- Antibody type:Primary
- Antigen name:Kappa Light Chain
- Clonality:Monoclonal
- Clone:Kap-56
- Gene ID:Unigene ID: 449609
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:IGKC
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:50 μL
- Western blot:Yes
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75955-564
Specifications
About this item
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Type: Primary
Antigen: IGKC
Clonality: Monoclonal
Clone: Clone Kap-56
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human