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Specifications
- Antibody type:Primary
- Antigen name:Smooth Muscle Actin
- Clonality:Monoclonal
- Clone:ACTA2/791
- Gene ID:Unigene ID: 500483
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Human,Rat
- Antigen symbol:ACTA2
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:50 μL
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75974-208
- Supplier No.:BNUM0791-50
Specifications
About this item
Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Type: Primary
Antigen: ACTA2
Clonality: Monoclonal
Clone: ACTA2/791
Conjugation: Purified, BSA-free
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human, Rat