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Specifications
- Antibody type:Primary
- Antigen name:CD20
- Clonality:Monoclonal
- Clone:IGEL/773
- Gene ID:Unigene ID: 712553
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Human
- Antigen symbol:MS4A1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:50 μL
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75890-730
- Supplier No.:BNUM0773-50
Specifications
About this item
This antibody recognizes a protein of 30-33 kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkins disease, particularly of lymphocyte predominant type.
Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: IGEL/773
Conjugation: Purified, BSA-free
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human