About this item
This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Type: Primary
Antigen: NEFL
Clonality: Monoclonal
Clone: Clone NFL/736
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chicken, Cow, Human, Pig, Rat
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Specifications
- Catalog No:
- 75965-900
- 75965-902
- Antigen name:
- Neurofilament
- Neurofilament
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- NFL/736
- NFL/736
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 521461
- Unigene ID: 521461
- Isotype:
- IgG1
- IgG1