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Specifications
- Antibody type:Primary
- Antigen name:Cyclin A2
- Clonality:Monoclonal
- Clone:E67
- Gene ID:Unigene ID: 58974
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Green monkey,Monkey,Human,Bovine,Mink,Mouse
- Antigen symbol:CCNA2
- Conjugation:Unconjugated
- ImmunoFluorescence:Yes
- Size:50 μL
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75921-476
- Supplier No.:BNUM0673-50
Specifications
About this item
This antibody recognizes a protein of 54 kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
Type: Primary
Antigen: CCNA2
Clonality: Monoclonal
Clone: Clone E67
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Cow, Green monkey, Human, Mink, Monkey, Mouse