About this item
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellularscavenger receptor cysteine-rich(SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Type: Primary
Antigen: CD6
Clonality: Monoclonal
Clone: Clone C6/372
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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Specifications
- Catalog No:
- 75917-144
- 75917-142
- Antigen name:
- CD6
- CD6
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- C6/372
- C6/372
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 744366
- Unigene ID: 744366
- Isotype:
- IgG1
- IgG1