About this item
This antibody recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Type: Primary
Antigen: Not Applicable
Clonality: Monoclonal
Clone: Clone 7LE
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Mouse
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Specifications
- Catalog No:
- 75956-704
- 75956-706
- Antigen name:
- Lewis A
- Lewis A
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- 7LE
- 7LE
- Reactivity:
- Human, Mouse
- Human, Mouse
- Host:
- Mouse
- Mouse
- Isotype:
- IgG1 kappa
- IgG1 kappa