About this item
This antibody recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Type: Primary
Antigen: VCAM1
Clonality: Monoclonal
Clone: Clone 1.4C3
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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Specifications
- Catalog No:
- 75885-768
- 75885-770
- Antigen name:
- CD106 / VCAM1
- CD106 / VCAM1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- 1.4C3
- 1.4C3
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 109225
- Unigene ID: 109225
- Isotype:
- IgG1 kappa
- IgG1 kappa