About this item
This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Type: Primary
Antigen: BAX
Clonality: Monoclonal
Clone: Clone 2D2
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Monkey
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Specifications
- Catalog No:
- 75886-002
- 75886-004
- Antigen name:
- Bax
- Bax
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- 2D2
- 2D2
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 624291
- Unigene ID: 624291
- Isotype:
- IgG1
- IgG1