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Specifications
- Antibody type:Primary
- Antigen name:Tumor Necrosis Factor alpha
- Clonality:Monoclonal
- Clone:MP6-XT22
- Host:Rat
- Isotype:IgG1 kappa
- Reactivity:Mouse
- Antigen symbol:TNFA
- Conjugation:PE (Phycoerythrin)-Cy7®
- Flow cytometry:Yes
- Size:25 μg
- Form:liquid
- Antigen synonyms:Tumor Necrosis Factor alpha|DIF|Differentiation inducing factor|MCF|Necrosin|TNFSF2|Cachectin|Macrophage cytotoxic factor
- Cat. no.:75841-394
- Supplier No.:84422-77-25
Specifications
About this item
The MP6-XT22 monoclonal antibody specifically reacts with mouse tumor necrosis factor alpha (TNF-alpha), a 156 amino pro-inflammatory cytokine. It is secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. NF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. The MP6-XT22 is reported to neutralize the bioactivity of natural or recombinant TNF-alpha and is useful for intracellular immunofluorescent staining.
Type: Primary
Antigen: TNFA
Clonality: Monoclonal
Clone: MP6-XT22
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Rat
Isotype: IgG1, kappa
Reactivity: Mouse