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Specifications
- Antibody type:Primary
- Antigen name:T-cell receptor beta
- Clonality:Monoclonal
- Clone:H57-597
- Host:Armenian hamster
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:TCRB
- Conjugation:BG Violet 450
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:TCRb|TCRbeta|TCR-b|b-TCR
- Cat. no.:75843-656
- Supplier No.:89612-40-100
Specifications
About this item
The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR). The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Type: Primary
Antigen: TCRB
Clonality: Monoclonal
Clone: H57-597
Conjugation: BG Violet 450
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse