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Specifications
- Antibody type:Primary
- Antigen name:T-cell receptor beta
- Clonality:Monoclonal
- Clone:H57-597
- Host:Armenian hamster
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:TCRB
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:TCRb|TCRbeta|TCR-b|b-TCR
- Cat. no.:75843-654
- Supplier No.:89612-20-100
Specifications
About this item
The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR). The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.
Type: Primary
Antigen: TCRB
Clonality: Monoclonal
Clone: H57-597
Conjugation:
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse