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Specifications
- Antibody type:Primary
- Antigen name:Killer cell lectin-like receptor subfamily B, member 1
- Clonality:Monoclonal
- Clone:PK136
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:KLRB1
- Conjugation:Biotin
- Flow cytometry:Yes
- Size:500 μg
- Form:liquid
- Antigen synonyms:NKR-P1C|NKR-P1B|CD161c|Ly-55|CD161b|CD161
- Cat. no.:75842-626
- Supplier No.:83712-30-500
Specifications
About this item
The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C.The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.
Type: Primary
Antigen: KLRB1
Clonality: Monoclonal
Clone: PK136
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Mouse