To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Antigen name:Integrin subunit alpha 4
- Clonality:Monoclonal
- Clone:DATK32
- Host:Rat
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:ITGA4
- Conjugation:APC (Allophycocyanin)
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:LPAM-1|ITGA4|CD49d/β7|ITGB7
- Cat. no.:75842-586
- Supplier No.:83212-80-100
Specifications
About this item
The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa α4 and the 130 kDa β7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the α4β7 integrin heterodimer. α4β7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the α4β7 induces the α4β7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.
Type: Primary
Antigen: ITGA4
Clonality: Monoclonal
Clone: DATK32
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG2a, kappa
Reactivity: Mouse