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Specifications
- Antibody type:Primary
- Antigen name:CD54 (ICAM-1) (15.2)
- Clonality:Monoclonal
- Clone:15.2
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Antigen symbol:ICAM1
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:Ly-47|Intercellular adhesion molecule-1|ICAM1
- Cat. no.:75841-846
- Supplier No.:06611-20-100
Specifications
About this item
The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1). ICAM-1 is also known CD 54 and is expressed on non-hematopoietic cells of vascular endothelial, thymic epithelial, fibroblasts lineages, and on hematopoietic cells like macrophages, mitogen-stimulated T-lymphoblasts, dendritic cells in tonsils, lymph nodes and Peyer’s patches, and germinal center B cells.Inflammatory mediators (IL-1, TNF, IFN-γ) enhance the production of ICAM-1 on fibroblasts and endothelial cells within few hours. Thus, ICAM-1 seems to be the marker of inflammatory reactions.
Type: Primary
Antigen: ICAM1
Clonality: Monoclonal
Clone: 15.2
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human