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Specifications
- Antibody type:Primary
- Antigen name:Fc epsilon Receptor I alpha (FceR1) (MAR-1)
- Clonality:Monoclonal
- Clone:42795
- Host:Armenian hamster
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:Fc epsilon Receptor I alpha (FceR1) (MAR-1)
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:FceRIa|high affinity IgE receptor
- Cat. no.:75841-368
- Supplier No.:84112-60-100
Specifications
About this item
The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc ε Receptor I α subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
Type: Primary
Antigen: Fc epsilon Receptor I alpha (FceR1) (MAR-1)
Clonality: Monoclonal
Clone: 42795
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse