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Specifications
- Antibody type:Primary
- Antigen name:Cluster of Differentiation 8a
- Clonality:Monoclonal
- Clone:2.43
- Host:Rat
- Isotype:IgG2b
- Reactivity:Mouse
- Antigen symbol:CD8a
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow cytometry:Yes
- Size:25 μg
- Form:liquid
- Antigen synonyms:T8|CD8 alpha|Ly-2|Lyt-2|Ly-35|Ly-B
- Cat. no.:75842-056
- Supplier No.:10112-50-25
Specifications
About this item
The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells.
Type: Primary
Antigen: CD8a
Clonality: Monoclonal
Clone: 2.43
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse