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Specifications
- Antibody type:Primary
- Antigen name:CD86 (B7-2) (PO3.1)
- Clonality:Monoclonal
- Clone:PO3.1
- Host:Rat
- Isotype:IgG2b kappa
- Reactivity:Mouse
- Antigen symbol:CD86 (B7-2) (PO3.1)
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:25 μg
- Form:liquid
- Antigen synonyms:B70|Ly-58|B7-2
- Cat. no.:75843-028
- Supplier No.:08922-60-25
Specifications
About this item
The PO3.1 monoclonal antibody specifically reacts with CD86, also known as B7-2, a surface 80 kDa receptor and member of the B7 family. CD86 is a costimulatory molecule, expressed on B and T cells, dendritic cells, astrocytes, macrophages, Langerhans cells, and at a low level in newly explanted B and T lymphocytes. CD86 expression on B lymphocytes is upregulated by B-Cell Receptor complex, CD40 and certain cytokine receptors. CD80 (B7-1) and CD 86 (B7-2) are receptors for CD28 and CTLA-4, on the surface of T lymphocytes, enhancing the interactions between B and T cells.
Type: Primary
Antigen: CD86 (B7-2) (PO3.1)
Clonality: Monoclonal
Clone: PO3.1
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse