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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:HMa2
- Host:Armenian hamster
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:CD49b
- Flow cytometry:Yes
- Size:500 μg
- Format:SAFIRE Purified
- Form:liquid
- Antigen synonyms:VLA2|DX5|Integrin a 2 chain
- Cat. no.:75842-198
- Supplier No.:11512-25-500
Specifications
About this item
The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1). VLA-2 is expressed on NK-T cells, epithelial cells, platelets, and CD+4 T lymphocytes. It is the receptor for laminin and collagen and is upregulated in response to mitogens. The Hma2 antibody is reported to partially block the interaction with collagen in T cells, but not NK cells.
Type: Primary
Antigen: CD49b
Clonality: Monoclonal
Clone: HMa2
Conjugation:
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse