To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:A20
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:CD45.1
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:25 μg
- Form:liquid
- Antigen synonyms:SJL|T200|LCA|Ly5.1
- Cat. no.:75844-142
- Supplier No.:07522-60-25
Specifications
About this item
The A20 monoclonal antibody reacts with the leukocytes of the CD45.1-expressing mouse strains (DA, SJL/J, RIII, and STS/A). It does not cross-react with cells that express CD45.2. The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction. The A20 antibody inhibits some of the B lymphocytes responses, from CD45.1-expressing mice, to lipopolysaccharides and antigens.
Type: Primary
Antigen: CD45.1
Clonality: Monoclonal
Clone: A20
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Mouse