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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:HM40-3
- Host:Armenian hamster
- Isotype:IgM kappa
- Reactivity:Mouse
- Antigen symbol:CD40
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow cytometry:Yes
- Size:50 μg
- Form:liquid
- Antigen synonyms:TNFRSF5
- Cat. no.:75843-692
- Supplier No.:02512-50-50
Specifications
About this item
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Type: Primary
Antigen: CD40
Clonality: Monoclonal
Clone: HM40-3
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Armenian Hamster
Isotype: IgM, kappa
Reactivity: Mouse