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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:5C3
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:CD40
- Conjugation:APC (Allophycocyanin)
- Flow cytometry:Yes
- Size:100 tests
- Form:liquid
- Antigen synonyms:TNFRSF5
- Cat. no.:75842-772
- Supplier No.:02511-80-100
Specifications
About this item
The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
Type: Primary
Antigen: CD40
Clonality: Monoclonal
Clone: 5C3
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human