To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:RPA-T4
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:CD4
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:Leu-3|L3T4|T4
- Cat. no.:75843-990
- Supplier No.:06121-20-100
Specifications
About this item
The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: RPA-T4
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human