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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:RM4-5
- Host:Rat
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:CD4
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:Leu-3|L3T4|T4
- Cat. no.:75844-036
- Supplier No.:06122-60-100
Specifications
About this item
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: RM4-5
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2a, kappa
Reactivity: Mouse