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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:RPA-T4
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:CD4
- Conjugation:BG Violet 450
- Flow cytometry:Yes
- Size:100 tests
- Form:liquid
- Antigen synonyms:Leu-3|L3T4|T4
- Cat. no.:75843-992
- Supplier No.:06121-40-100
Specifications
About this item
The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: RPA-T4
Conjugation: BG Violet 450
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human