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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:37.51
- Host:Golden syrian hamster
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:CD28
- Flow cytometry:Yes
- Size:500 μg
- Format:SAFIRE Purified
- Form:liquid
- Antigen synonyms:Tp44|T44
- Cat. no.:75844-302
- Supplier No.:10312-25-500
Specifications
About this item
The 37.51 monoclonal antibody specifically reacts with mouse CD28 molecule, a 45 kDa homodimer. It is expressed on most thymocytes, at low density on most of the CD4+ and CD8+ peripheral T lymphocytes, and on the natural killer cells. It is additionally found on activated splenocytes, mast cells, and thymocytes. CD 28 is a costimulator of T lymphocytes and a ligand for CD80 (B7-1), and CD86 (B7-2). The CD28 signaling stimulates the expression of IL-2 and IL-2 receptor and the cytotoxicity of CD3-activated T lymphocytes.The 37.51 antibody stimulates the proliferation of T lymphocytes and natural killer cells and their respective cytokine production.
Type: Primary
Antigen: CD28
Clonality: Monoclonal
Clone: 37.51
Conjugation:
Epitope:
Host: Golden Syrian Hamster
Isotype: IgG
Reactivity: Mouse