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Specifications
- Antibody type:Primary
- Antigen name:CD278 (ICOS)
- Clonality:Monoclonal
- Clone:ISA-3
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:CD278
- Conjugation:PE (Phycoerythrin)-Cy7®
- Flow cytometry:Yes
- Size:100 tests
- Form:liquid
- Antigen synonyms:AILIM|H4|CRP-1
- Cat. no.:75842-394
- Supplier No.:30811-77-100
Specifications
About this item
The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS), a 47-60 kDA homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4,5,10 in T cells.
Type: Primary
Antigen: CD278
Clonality: Monoclonal
Clone: ISA-3
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human