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Specifications
- Antibody type:Primary
- Antigen name:CD274 (PD-L1, B7-H1) (10F.9G2)
- Clonality:Monoclonal
- Clone:10F.9G2
- Host:Rat
- Isotype:IgG2b kappa
- Reactivity:Mouse
- Antigen symbol:CD274
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:PDL1|B7H1
- Cat. no.:75842-366
- Supplier No.:26812-60-100
Specifications
About this item
The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.
Type: Primary
Antigen: CD274
Clonality: Monoclonal
Clone: 10F.9G2
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse