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Specifications
- Antibody type:Primary
- Antigen name:Interleukin-2 receptor alpha chain
- Clonality:Monoclonal
- Clone:PC61.5
- Host:Rat
- Isotype:IgG lambda
- Reactivity:Mouse
- Antigen symbol:IL2RA
- Conjugation:PE (Phycoerythrin)-Cy7®
- Flow cytometry:Yes
- Size:25 μg
- Form:liquid
- Antigen synonyms:IMD41|TCGFR|p55|interleukin 2 receptor subunit alpha|IL2R|IDDM10|CD25|IL2RA
- Cat. no.:75841-956
- Supplier No.:07312-77-25
Specifications
About this item
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor β) and CD 132 (IL-2 Receptor γc, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Rα. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody blocks the binding of IL-2 to both high-affinity and low-affinity receptors.
Type: Primary
Antigen: IL2RA
Clonality: Monoclonal
Clone: PC61.5
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Rat
Isotype: IgG1, lambda
Reactivity: Mouse