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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:1D3
- Host:Rat
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:CD19
- Conjugation:PE (Phycoerythrin)-Cy7®
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:B4 |Leu-12
- Cat. no.:75842-146
- Supplier No.:11212-77-100
Specifications
About this item
The 1D3 monoclonal antibody specifically reacts with MouseCD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.
Type: Primary
Antigen: CD19
Clonality: Monoclonal
Clone: 1D3
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Rat
Isotype: IgG2a, kappa
Reactivity: Mouse