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Specifications
- Antibody type:Primary
- Antigen name:CD40 Ligand
- Clonality:Monoclonal
- Clone:MR1
- Host:Armenian hamster
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:CD154
- Conjugation:Biotin
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Cat. no.:75842-292
- Supplier No.:16612-30-100
Specifications
About this item
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Type: Primary
Antigen: CD154
Clonality: Monoclonal
Clone: MR1
Conjugation: Biotin
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse