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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:61D3
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:CD14
- Conjugation:BG Violet 450
- Flow cytometry:Yes
- Size:100 tests
- Form:liquid
- Antigen synonyms:Mo2|LPS-R
- Cat. no.:75841-742
- Supplier No.:06211-40-100
Specifications
About this item
The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Type: Primary
Antigen: CD14
Clonality: Monoclonal
Clone: 61D3
Conjugation: BG Violet 450
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human