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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:M17/4
- Host:Rat
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:CD11a
- Flow cytometry:Yes
- Size:100 μg
- Format:SAFIRE Purified
- Form:liquid
- Antigen synonyms:LFA-1alpha|Integrin alpha L chain
- Cat. no.:75842-806
- Supplier No.:03222-25-100
Specifications
About this item
The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
Type: Primary
Antigen: CD11a
Clonality: Monoclonal
Clone: M17/4
Conjugation:
Epitope:
Host: Rat
Isotype: IgG2a, kappa
Reactivity: Mouse