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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:ACK2
- Host:Rat
- Isotype:IgG2b kappa
- Reactivity:Mouse
- Antigen symbol:CD117 (c-Kit) (ACK2)
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:SCFR|cKit|Steel Factor Receptor
- Cat. no.:75844-438
- Supplier No.:19112-60-100
Specifications
About this item
The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
Type: Primary
Antigen: CD117 (c-Kit) (ACK2)
Clonality: Monoclonal
Clone: ACK2
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse