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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:H74
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:B7-H4
- Flow cytometry:Yes
- Size:100 μg
- Format:SAFIRE Purified
- Form:liquid
- Antigen synonyms:B7H4|B7S1|VTCN1|B7X
- Cat. no.:75843-650
- Supplier No.:86611-25-100
Specifications
About this item
The H74 monoclonal antibody binds to human B7-H4, a newly discovered member of the B7 family involved with the negative regulation of T cell immunity. B7-H4 is a type I membrane glycoprotein also known as B7S1, B7X, and VCTN1. Its role in tumor progression may be to protect precancerous cells from the surveillance of the immune system. Further studies are being conducted to determine the exact B7-H4 ligand. It is reported that the H74 antibody binds to human B7-H4 transfected cells and not peripheral blood cells.
Type: Primary
Antigen: B7-H4
Clonality: Monoclonal
Clone: H74
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human