About this item
Resistin-like molecule-beta (RELM-b) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. The RELM family consists of Resistin (FIZZ3), RELM-a (FIZZ1), RELM-b (FIZZ2), and RELM-g (FIZZ4). Resistin and RELM-b are the only RELM family members found in humans, whereas all four RELM family members are present in rodents. RELM-b functions to increase fibroblast proliferation and differentiation, resulting in airway remodelling and increased inflammation.
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