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Specifications
- Enzyme type:Recombinant
- Source:E. coli
- Species:H. influenzae
- Size:50 μg
- Storage conditions:Stable for at least 6 months after receipt when stored at –80 °C.
- Enzyme name:NAD Nucleotidase
- Enzyme activity:With AMP: 856.4 nmol of Ade/min/mg of protein
With NMN: 110,3 nmol of NR/min/mg of protein
With NAD: 5.4 nmol of Ade/min per mg of protein | 5.3 nmol of NR/min/mg of protein - Enzyme synonyms:NadN, NAD Pyrophosphatase/5'-nucleotidase
- Purity:>98% (SDS-PAGE)
- Sequence:Full-length NAD 5’-nucleotidase without the signal peptide corresponding to the first 26 aa
- Formulation:Liquid, In 5mM KH₂PO₄, pH 6.8 containing 100 mM TRIS-HCl (pH 8.5) and 10 mM MgCl₂.
- Cat. no.:75794-330
- Supplier No.:90-368
Specifications
About this item
NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement
This recombinant proteins is for research use only.
Fusion-Tag: Tag Free
NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5'-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi | AMP=Ade+Pi | NMN=NR+Pi