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Specifications
- Protein/peptide type:Recombinant
- Source:Insect cells (Sf21)
- Species:Mouse
- Size:2 μg
- Tag sequence:His Tag
- Storage conditions:Stable for at least 6 months after receipt when stored at −80 °C.
- Biological activity:~50-100ng are required for standard HAT assay.
- Protein synonyms:CBP|CREBBP
- Protein/peptide name:CREB-binding highly active
- Purity:>95% (SDS-PAGE)
- Formulation:Liquid, In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol.
- Cat. no.:75794-154
- Supplier No.:90-344
Specifications
About this item
CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.
- Fusion-Tag: His Tag
This recombinant proteins is for research use only.