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TNF RII Recombinant Protein, Prosci
TNF RII Recombinant Protein, Prosci
Catalog #: 75791-962
Supplier:  Prosci
CAS Number:  
TNF RII Recombinant Protein, Prosci
Catalog #: 75791-962
Supplier:  Prosci
CAS Number:  
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Specifications

  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-Fc tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    CD120b|Tumor necrosis factor receptor superfamily member 1B|TNFRSF1B|p75|p80 TNF-alpha receptor|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor 2|TNF-RII
  • Protein/peptide name:
    TNF Receptor II
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    51.9 kD
  • Sequence:
    Leu23-Asp257
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH4O. Please aliquot the reconstituted solution toPTTLGTIHSPEDVIKALADHHHHHHHHHE
  • Cat. no.:
    75791-962
  • Supplier No.:
    92-700

Specifications

About this item

Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino acid sequence identity with the mouse and rat orthologs, respectively.TNF RII is expressed predominantly on cells of the hematopoietic lineage, such as T and natural killer cells, as well as on endothelial cells, microglia, astrocytes,neurons, oligodendrocytes, cardiac myocytes, thymocytes, and mesenchymal stem cells.TNF RII binds to the membranebound forms of TNF alpha and Lymphotoxin alpha/TNF beta ;soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNF biological activity by binding TNF thereby preventing it from activating membrane TNF receptors.

  • Fusion-Tag: C-Fc tag

This recombinant protein can be used for biological assays. For research use only.

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