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Specifications
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Size:0.05 mg
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Endotoxin content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein synonyms:6-P2ase liver isozyme|PFKFB1|F6PK|6PF-2-K/Fru-2|6-phosphofructo-2-kinase/fructose-2|Fructose-2|PFK|6-bisphosphatase 1|6-bisphosphatase|FBPase 1|PFRX
- Protein/peptide name:PFKFB1
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:55.6 kD
- Sequence:Ser2-Tyr471
- Formulation:Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
- Cat. no.:75791-286
- Supplier No.:92-350
Specifications
About this item
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.