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Specifications
- Enzyme type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.05 mg
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Endotoxin content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Enzyme name:Aldo-Keto Reductase 1C3
- Enzyme synonyms:Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1, 2-Dihydrobenzene-1, 2-Diol Dehydrogenase, Type III 3-Alpha-Hydroxysteroid Dehydrogenase, AKR1C2, DDH2
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:36.74 kD
- Sequence:Met1-Tyr323
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
- Cat. no.:75789-226
- Supplier No.:91-275
Specifications
About this item
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5- alpha/5- beta -Steroid Reductases to convert Steroid hormones into the 3- alpha/5- alpha and 3- alpha/5- beta -Tetrahydrosteroids
This recombinant protein can be used for biological assays. For research use only.
AKR1C2 catalyzes the inactivation of the most potent androgen 5- alpha-Dihydrotestosterone (5- alpha-DHT) to 5- alpha-Androstane-3- alpha, 17- beta -diol (3- alpha-diol).