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Specifications
- Enzyme type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.05 mg
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Endotoxin content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Enzyme name:PPIase H
- Enzyme synonyms:Peptidyl-Prolyl Cis-Trans Isomerase H, PPIase H, Rotamase H, Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H, CypH, U-snRNP-Associated Cyclophilin SnuCyp-20, USA-CYP, PPIH, CYP20
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:21.4 kD
- Sequence:Met1-Met177
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
- Cat. no.:75789-182
- Supplier No.:91-233
Specifications
About this item
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins
This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-6 His tag
PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.