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Specifications
- Antibody type:Primary
- Antigen name:peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- Clonality:Polyclonal
- Gene ID:Q13526
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PIN1
- Conjugation:Unconjugated
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:PIN1
- Modification:Ser 16
- Storage buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular weight:18 kDa
- Storage temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:Pin1 (phospho Ser16) antibody was raised against a peptide sequence around phosphorylation site of serine16 (R-M-S (p)-R-S) derived from Human Pin1 .
- Purification:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Cat. no.:10814-208
- Supplier No.:80-010
Specifications
About this item
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
Western Blot: 1:500~1:1000
Type: Primary
Antigen: PIN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat